G817-0265 Screening compound: 4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline

G817-0265 Screening compound: 4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline
G817-0265 Screening compound: 4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound G817-0265
4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G817-0265

Molecular Formula

C25H28N4O3 (C25 H28 N4 O3)

Compound Name

4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline

IUPAC name

4-[4-(2-methoxyphenyl)piperazine-1-carbonyl]-1-(morpholin-4-yl)isoquinoline

SMILES

COc(cccc1)c1N(CC1)CCN1C(c(c1ccccc11)cnc1N1CCOCC1)=O

InChI

InChI=1S/C25H28N4O3/c1-31-23-9-5-4-8-22(23)27-10-12-29(13-11-27)25(30)21-18-26-24(28-14-16-32-17-15-28)20-7-3-2-6-19(20)21/h2-9,18H,10-17H2,1H3

InChI Key

NMCLSIVOYKIJPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15038717

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.429

Distribution Coefficient, logD

3.420

Water Solubility, LogSw

-3.52

Polar Surface Area

47.636

Acid Dissociation Constant (pKa)

23.86

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

G817-0265 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

CNS targets activity set (6557 compounds)

PI3K-Targeted Library (17255 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G817-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G817-0265?
Check Price and Availability of G817-0265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G817-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G817-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G817-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G817-0265 available by request