G819-0245 Screening compound: N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide

G819-0245 Screening compound: N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide
G819-0245 Screening compound: N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G819-0245
N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G819-0245

Molecular Formula

C22H22N4O3S (C22 H22 N4 O3 S)

Compound Name

N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide

IUPAC name

N-[2-(furan-2-yl)ethyl]-2-{[1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl]methanesulfinyl}acetamide

SMILES

O=C(CS(Cc1c(-n2cccc2)n(-c2ccccc2)nc1)=O)NCCc1ccco1

InChI

InChI=1S/C22H24N4O3S/c27-21(23-11-10-20-9-6-14-29-20)17-30(28)16-18-15-24-26(19-7-2-1-3-8-19)22(18)25-12-4-5-13-25/h1-9,12-15H,10-11,16-17,30H2,(H,23,27)

InChI Key

SZUHGLMQUQMWNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15039024

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.744

Distribution Coefficient, logD

2.744

Water Solubility, LogSw

-3.14

Polar Surface Area

63.929

Acid Dissociation Constant (pKa)

13.82

Base Dissociation Constant (pKb)

1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

G819-0245 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G819-0245 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G819-0245?
Check Price and Availability of G819-0245, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G819-0245 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G819-0245
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G819-0245
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G819-0245 available by request