G827-0021 Screening compound: 3-(3,5-dimethyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide

G827-0021 Screening compound: 3-(3,5-dimethyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide
G827-0021 Screening compound: 3-(3,5-dimethyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G827-0021
3-(3,5-dimethyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G827-0021

Molecular Formula

C19H18FN7O (C19 H18 FN7 O)

Compound Name

3-(3,5-dimethyl-1-{[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide

IUPAC name

3-(35-dimethyl-1-{[124]triazolo[43-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-(3-fluorophenyl)propanamide

SMILES

Cc1c(CCC(Nc2cccc(F)c2)=O)c(C)nn1-c(cc1)nn2c1nnc2

InChI

InChI=1S/C19H18FN7O/c1-12-16(6-9-19(28)22-15-5-3-4-14(20)10-15)13(2)27(24-12)18-8-7-17-23-21-11-26(17)25-18/h3-5,7-8,10-11H,6,9H2,1-2H3,(H,22,28)

InChI Key

ZPMPNTDJMSNRIM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27163557

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.865

Distribution Coefficient, logD

1.865

Water Solubility, LogSw

-2.45

Polar Surface Area

70.079

Acid Dissociation Constant (pKa)

10.50

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

G827-0021 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G827-0021 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G827-0021?
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What is the minimum amount of G827-0021 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G827-0021
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G827-0021
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G827-0021 available by request