G827-0199 Screening compound: N-(2,5-difluorophenyl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide

G827-0199 Screening compound: N-(2,5-difluorophenyl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide
G827-0199 Screening compound: N-(2,5-difluorophenyl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G827-0199
N-(2,5-difluorophenyl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G827-0199

Molecular Formula

C20H19F2N7O (C20 H19 F2 N7 O)

Compound Name

N-(2,5-difluorophenyl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide

IUPAC name

N-(25-difluorophenyl)-3-(35-dimethyl-1-{3-methyl-[124]triazolo[43-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propanamide

SMILES

Cc1c(CCC(Nc(cc(cc2)F)c2F)=O)c(C)nn1-c(cc1)nn2c1nnc2C

InChI

InChI=1S/C20H19F2N7O/c1-11-15(5-9-20(30)23-17-10-14(21)4-6-16(17)22)12(2)28(26-11)19-8-7-18-25-24-13(3)29(18)27-19/h4,6-8,10H,5,9H2,1-3H3,(H,23,30)

InChI Key

PIGOUIUPYCEIPU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27163673

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.896

Distribution Coefficient, logD

1.870

Water Solubility, LogSw

-2.56

Polar Surface Area

69.507

Acid Dissociation Constant (pKa)

8.62

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

G827-0199 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G827-0199 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G827-0199?
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What is the minimum amount of G827-0199 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G827-0199
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G827-0199
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G827-0199 available by request