G827-0212 Screening compound: 3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide

G827-0212 Screening compound: 3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide
G827-0212 Screening compound: 3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G827-0212
3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G827-0212

Molecular Formula

C20H23N7O2 (C20 H23 N7 O2)

Compound Name

3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide

IUPAC name

3-(35-dimethyl-1-{3-methyl-[124]triazolo[43-b]pyridazin-6-yl}-1H-pyrazol-4-yl)-N-[(5-methylfuran-2-yl)methyl]propanamide

SMILES

Cc1ccc(CNC(CCc2c(C)n(-c(cc3)nn4c3nnc4C)nc2C)=O)o1

InChI

InChI=1S/C20H23N7O2/c1-12-5-6-16(29-12)11-21-20(28)10-7-17-13(2)24-26(14(17)3)19-9-8-18-23-22-15(4)27(18)25-19/h5-6,8-9H,7,10-11H2,1-4H3,(H,21,28)

InChI Key

XIUUXZQIRQMKMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27163683

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.486

Distribution Coefficient, logD

1.486

Water Solubility, LogSw

-1.98

Polar Surface Area

78.790

Acid Dissociation Constant (pKa)

12.69

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

G827-0212 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G827-0212 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G827-0212?
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What is the minimum amount of G827-0212 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G827-0212
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G827-0212
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G827-0212 available by request