G843-0469 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide

G843-0469 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide
G843-0469 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G843-0469
1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G843-0469

Molecular Formula

C20H13ClF4N2O2 (C20 H13 ClF4 N2 O2)

Compound Name

1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide

IUPAC name

1-[(2-chloro-6-fluorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-16-dihydropyridine-3-carboxamide

SMILES

O=C(C(C=C1)=CN(Cc(c(F)ccc2)c2Cl)C1=O)Nc1ccc(C(F)(F)F)cc1

InChI

InChI=1S/C20H13ClF4N2O2/c21-16-2-1-3-17(22)15(16)11-27-10-12(4-9-18(27)28)19(29)26-14-7-5-13(6-8-14)20(23,24)25/h1-10H,11H2,(H,26,29)

InChI Key

MOEJHNNZQYJTKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09247591

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.78

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.191

Distribution Coefficient, logD

4.183

Water Solubility, LogSw

-4.49

Polar Surface Area

39.841

Acid Dissociation Constant (pKa)

9.13

Base Dissociation Constant (pKb)

-1.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G843-0469 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G843-0469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G843-0469?
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What is the minimum amount of G843-0469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G843-0469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G843-0469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G843-0469 available by request