G843-0511 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

G843-0511 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-1,6-dihydropyridine-3-carboxamide
G843-0511 Screening compound: 1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-1,6-dihydropyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G843-0511
1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G843-0511

Molecular Formula

C20H12ClF5N2O2 (C20 H12 ClF5 N2 O2)

Compound Name

1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

IUPAC name

1-[(2-chloro-6-fluorophenyl)methyl]-N-[4-fluoro-3-(trifluoromethyl)phenyl]-6-oxo-16-dihydropyridine-3-carboxamide

SMILES

O=C(C(C=C1)=CN(Cc(c(F)ccc2)c2Cl)C1=O)Nc(cc1)cc(C(F)(F)F)c1F

InChI

InChI=1S/C20H12ClF5N2O2/c21-15-2-1-3-16(22)13(15)10-28-9-11(4-7-18(28)29)19(30)27-12-5-6-17(23)14(8-12)20(24,25)26/h1-9H,10H2,(H,27,30)

InChI Key

OVTHSSSHFSFKNP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09247616

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.77

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.367

Distribution Coefficient, logD

2.014

Water Solubility, LogSw

-4.59

Polar Surface Area

39.841

Acid Dissociation Constant (pKa)

5.05

Base Dissociation Constant (pKb)

-0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G843-0511 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G843-0511 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G843-0511?
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What is the minimum amount of G843-0511 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G843-0511
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G843-0511
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G843-0511 available by request