G843-0848 Screening compound: N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

G843-0848 Screening compound: N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide
G843-0848 Screening compound: N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G843-0848
N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G843-0848

Molecular Formula

C20H17FN2O2 (C20 H17 FN2 O2)

Compound Name

N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide

IUPAC name

N-(3-fluorophenyl)-1-[(4-methylphenyl)methyl]-6-oxo-16-dihydropyridine-3-carboxamide

SMILES

Cc1ccc(CN(C=C(C=C2)C(Nc3cccc(F)c3)=O)C2=O)cc1

InChI

InChI=1S/C20H17FN2O2/c1-14-5-7-15(8-6-14)12-23-13-16(9-10-19(23)24)20(25)22-18-4-2-3-17(21)11-18/h2-11,13H,12H2,1H3,(H,22,25)

InChI Key

LILAKZJDKIKOGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07805712

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

336.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.106

Distribution Coefficient, logD

2.791

Water Solubility, LogSw

-3.20

Polar Surface Area

39.841

Acid Dissociation Constant (pKa)

7.37

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

G843-0848 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G843-0848 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G843-0848?
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What is the minimum amount of G843-0848 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G843-0848
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G843-0848
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G843-0848 available by request