G843-1674 Screening compound: N-(2,4-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

G843-1674 Screening compound: N-(2,4-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide
G843-1674 Screening compound: N-(2,4-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G843-1674
N-(2,4-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G843-1674

Molecular Formula

C22H19F3N2O4 (C22 H19 F3 N2 O4)

Compound Name

N-(2,4-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

IUPAC name

N-(24-dimethoxyphenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-16-dihydropyridine-3-carboxamide

SMILES

COc(cc1)cc(OC)c1NC(C(C=C1)=CN(Cc2ccc(C(F)(F)F)cc2)C1=O)=O

InChI

InChI=1S/C22H19F3N2O4/c1-30-17-8-9-18(19(11-17)31-2)26-21(29)15-5-10-20(28)27(13-15)12-14-3-6-16(7-4-14)22(23,24)25/h3-11,13H,12H2,1-2H3,(H,26,29)

InChI Key

IEJSWZFZSYQKTB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09247883

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.345

Distribution Coefficient, logD

3.083

Water Solubility, LogSw

-3.63

Polar Surface Area

54.317

Acid Dissociation Constant (pKa)

7.48

Base Dissociation Constant (pKb)

2.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

G843-1674 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G843-1674 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G843-1674?
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What is the minimum amount of G843-1674 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G843-1674
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G843-1674
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G843-1674 available by request