G843-1708 Screening compound: N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

G843-1708 Screening compound: N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide
G843-1708 Screening compound: N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G843-1708
N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G843-1708

Molecular Formula

C22H18F3N3O3 (C22 H18 F3 N3 O3)

Compound Name

N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyridine-3-carboxamide

IUPAC name

N-(3-acetamidophenyl)-6-oxo-1-{[4-(trifluoromethyl)phenyl]methyl}-16-dihydropyridine-3-carboxamide

SMILES

CC(Nc1cccc(NC(C(C=C2)=CN(Cc3ccc(C(F)(F)F)cc3)C2=O)=O)c1)=O

InChI

InChI=1S/C22H18F3N3O3/c1-14(29)26-18-3-2-4-19(11-18)27-21(31)16-7-10-20(30)28(13-16)12-15-5-8-17(9-6-15)22(23,24)25/h2-11,13H,12H2,1H3,(H,26,29)(H,27,31)

InChI Key

WCMXDYRBAMARSQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09247889

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.606

Distribution Coefficient, logD

2.605

Water Solubility, LogSw

-2.98

Polar Surface Area

63.103

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

-0.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

G843-1708 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

CORONAVIRUS Library (20774 compounds)

GABA Library (7115 compounds)

PLpro Library (6343 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Eye
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G843-1708 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G843-1708?
Check Price and Availability of G843-1708, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G843-1708 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G843-1708
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G843-1708
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G843-1708 available by request