G851-0189 Screening compound: N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H,9H,10H,11H-cycloocta[b]indole-2-sulfonamide

G851-0189 Screening compound: N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H,9H,10H,11H-cycloocta[b]indole-2-sulfonamide
G851-0189 Screening compound: N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H,9H,10H,11H-cycloocta[b]indole-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-0189
N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H,9H,10H,11H-cycloocta[b]indole-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-0189

Molecular Formula

C22H26N2O4S (C22 H26 N2 O4 S)

Compound Name

N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H,9H,10H,11H-cycloocta[b]indole-2-sulfonamide

IUPAC name

N-(35-dimethoxyphenyl)-5H6H7H8H9H10H11H-cycloocta[b]indole-2-sulfonamide

SMILES

COc1cc(NS(c(cc2)cc3c2[nH]c2c3CCCCCC2)(=O)=O)cc(OC)c1

InChI

InChI=1S/C22H26N2O4S/c1-27-16-11-15(12-17(13-16)28-2)24-29(25,26)18-9-10-22-20(14-18)19-7-5-3-4-6-8-21(19)23-22/h9-14,23-24H,3-8H2,1-2H3

InChI Key

NSUAALIQDPWVHE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040309

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.637

Distribution Coefficient, logD

3.775

Water Solubility, LogSw

-4.49

Polar Surface Area

67.077

Acid Dissociation Constant (pKa)

6.60

Base Dissociation Constant (pKb)

-3.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

G851-0189 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

CNS targets activity set (6557 compounds)

DGK Inhibitors Library (10558 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G851-0189 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-0189?
Check Price and Availability of G851-0189, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-0189 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-0189
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-0189
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-0189 available by request