G851-0254 Screening compound: 1-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-3,3-dimethyl-5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indol-2-one

G851-0254 Screening compound: 1-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-3,3-dimethyl-5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indol-2-one
G851-0254 Screening compound: 1-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-3,3-dimethyl-5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-0254
1-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-3,3-dimethyl-5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-0254

Molecular Formula

C29H38N4O4S (C29 H38 N4 O4 S)

Compound Name

1-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-3,3-dimethyl-5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indol-2-one

IUPAC name

1-{2-[4-(23-dimethylphenyl)piperazin-1-yl]-2-oxoethyl}-33-dimethyl-5-(piperidine-1-sulfonyl)-23-dihydro-1H-indol-2-one

SMILES

CC(C)(c(cc(cc1)S(N2CCCCC2)(=O)=O)c1N1CC(N(CC2)CCN2c2c(C)c(C)ccc2)=O)C1=O

InChI

InChI=1S/C29H38N4O4S/c1-21-9-8-10-25(22(21)2)30-15-17-31(18-16-30)27(34)20-33-26-12-11-23(19-24(26)29(3,4)28(33)35)38(36,37)32-13-6-5-7-14-32/h8-12,19H,5-7,13-18,20H2,1-4H3

InChI Key

OCUZYIOYBKWDAB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040360

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

538.71

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.289

Distribution Coefficient, logD

4.289

Water Solubility, LogSw

-4.28

Polar Surface Area

66.770

Acid Dissociation Constant (pKa)

24.16

Base Dissociation Constant (pKb)

4.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

51.70

G851-0254 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G851-0254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-0254?
Check Price and Availability of G851-0254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-0254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-0254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-0254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-0254 available by request