G851-0265 Screening compound: methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate

G851-0265 Screening compound: methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate
G851-0265 Screening compound: methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-0265
methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-0265

Molecular Formula

C20H21ClN2O5S (C20 H21 ClN2 O5 S)

Compound Name

methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-1-yl)acetate

IUPAC name

methyl 2-(5-{[(2-chlorophenyl)methyl]sulfamoyl}-33-dimethyl-2-oxo-23-dihydro-1H-indol-1-yl)acetate

SMILES

CC(C)(c(cc(cc1)S(NCc(cccc2)c2Cl)(=O)=O)c1N1CC(OC)=O)C1=O

InChI

InChI=1S/C20H21ClN2O5S/c1-20(2)15-10-14(8-9-17(15)23(19(20)25)12-18(24)28-3)29(26,27)22-11-13-6-4-5-7-16(13)21/h4-10,22H,11-12H2,1-3H3

InChI Key

JVYSNIVEVDGWTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040371

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.92

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.332

Distribution Coefficient, logD

3.332

Water Solubility, LogSw

-3.63

Polar Surface Area

78.316

Acid Dissociation Constant (pKa)

10.51

Base Dissociation Constant (pKb)

-4.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G851-0265 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G851-0265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-0265?
Check Price and Availability of G851-0265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-0265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-0265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-0265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-0265 available by request