G851-0378 Screening compound: N-(2-methoxyethyl)-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-2,3-dihydro-1H-indole-1-carboxamide

G851-0378 Screening compound: N-(2-methoxyethyl)-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-2,3-dihydro-1H-indole-1-carboxamide
G851-0378 Screening compound: N-(2-methoxyethyl)-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-2,3-dihydro-1H-indole-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-0378
N-(2-methoxyethyl)-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-2,3-dihydro-1H-indole-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-0378

Molecular Formula

C21H25N3O4S (C21 H25 N3 O4 S)

Compound Name

N-(2-methoxyethyl)-5-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)-2,3-dihydro-1H-indole-1-carboxamide

IUPAC name

N-(2-methoxyethyl)-5-(1234-tetrahydroisoquinoline-2-sulfonyl)-23-dihydro-1H-indole-1-carboxamide

SMILES

COCCNC(N(CC1)c(cc2)c1cc2S(N(CC1)Cc2c1cccc2)(=O)=O)=O

InChI

InChI=1S/C21H25N3O4S/c1-28-13-10-22-21(25)24-12-9-17-14-19(6-7-20(17)24)29(26,27)23-11-8-16-4-2-3-5-18(16)15-23/h2-7,14H,8-13,15H2,1H3,(H,22,25)

InChI Key

MGWIGQQQABSWRB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040431

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.51

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.276

Distribution Coefficient, logD

3.276

Water Solubility, LogSw

-3.69

Polar Surface Area

65.889

Acid Dissociation Constant (pKa)

14.96

Base Dissociation Constant (pKb)

-1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

G851-0378 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G851-0378 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-0378?
Check Price and Availability of G851-0378, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-0378 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-0378
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-0378
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-0378 available by request