G851-0532 Screening compound: 1-[4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOYL]-4-(PIPERIDINE-1-CARBONYL)PIPERIDINE

G851-0532 Screening compound: 1-[4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOYL]-4-(PIPERIDINE-1-CARBONYL)PIPERIDINE
G851-0532 Screening compound: 1-[4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOYL]-4-(PIPERIDINE-1-CARBONYL)PIPERIDINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-0532
1-[4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOYL]-4-(PIPERIDINE-1-CARBONYL)PIPERIDINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-0532

Molecular Formula

C21H26N4O3 (C21 H26 N4 O3)

Compound Name

1-[4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOYL]-4-(PIPERIDINE-1-CARBONYL)PIPERIDINE

IUPAC name

1-[4-(5-methyl-124-oxadiazol-3-yl)benzoyl]-4-(piperidine-1-carbonyl)piperidine

SMILES

Cc1nc(-c(cc2)ccc2C(N(CC2)CCC2C(N2CCCCC2)=O)=O)no1

InChI

InChI=1S/C21H26N4O3/c1-15-22-19(23-28-15)16-5-7-17(8-6-16)20(26)25-13-9-18(10-14-25)21(27)24-11-3-2-4-12-24/h5-8,18H,2-4,9-14H2,1H3

InChI Key

BRXWUAMQRGSLEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27164587

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.46

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.351

Distribution Coefficient, logD

2.351

Water Solubility, LogSw

-2.52

Polar Surface Area

64.440

Acid Dissociation Constant (pKa)

23.62

Base Dissociation Constant (pKb)

0.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.38

G851-0532 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

MCE-18 Trends in Medicinal Chemistry (51288 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G851-0532 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-0532?
Check Price and Availability of G851-0532, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-0532 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-0532
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-0532
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-0532 available by request