G851-1027 Screening compound: 1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine

G851-1027 Screening compound: 1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine
G851-1027 Screening compound: 1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-1027
1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-1027

Molecular Formula

C18H18N4O2S (C18 H18 N4 O2 S)

Compound Name

1-[4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine

IUPAC name

1-[4-(5-methyl-124-oxadiazol-3-yl)phenyl]-4-(thiophene-2-carbonyl)piperazine

SMILES

Cc1nc(-c(cc2)ccc2N(CC2)CCN2C(c2cccs2)=O)no1

InChI

InChI=1S/C18H18N4O2S/c1-13-19-17(20-24-13)14-4-6-15(7-5-14)21-8-10-22(11-9-21)18(23)16-3-2-12-25-16/h2-7,12H,8-11H2,1H3

InChI Key

XITPQXWZHCDFNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27164745

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

354.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.326

Distribution Coefficient, logD

3.326

Water Solubility, LogSw

-3.39

Polar Surface Area

52.071

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

0.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G851-1027 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G851-1027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-1027?
Check Price and Availability of G851-1027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-1027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-1027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-1027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-1027 available by request