G851-1166 Screening compound: 1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one

G851-1166 Screening compound: 1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one
G851-1166 Screening compound: 1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G851-1166
1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G851-1166

Molecular Formula

C24H33N5O2 (C24 H33 N5 O2)

Compound Name

1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one

IUPAC name

1-(4-cyclohexylpiperazin-1-yl)-2-[3-(pyrrolidine-1-carbonyl)-1H-indazol-1-yl]ethan-1-one

SMILES

O=C(Cn1nc(C(N2CCCC2)=O)c2c1cccc2)N(CC1)CCN1C1CCCCC1

InChI

InChI=1S/C24H33N5O2/c30-22(27-16-14-26(15-17-27)19-8-2-1-3-9-19)18-29-21-11-5-4-10-20(21)23(25-29)24(31)28-12-6-7-13-28/h4-5,10-11,19H,1-3,6-9,12-18H2

InChI Key

IPEJDEORALINGN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27164831

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.369

Distribution Coefficient, logD

2.206

Water Solubility, LogSw

-2.50

Polar Surface Area

50.717

Acid Dissociation Constant (pKa)

24.87

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

62.50

G851-1166 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G851-1166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G851-1166?
Check Price and Availability of G851-1166, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G851-1166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G851-1166
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G851-1166
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G851-1166 available by request