G852-0205 Screening compound: 6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-1,2-dihydroquinolin-2-one

G852-0205 Screening compound: 6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-1,2-dihydroquinolin-2-one
G852-0205 Screening compound: 6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G852-0205
6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G852-0205

Molecular Formula

C21H31N3O4S (C21 H31 N3 O4 S)

Compound Name

6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-1,2-dihydroquinolin-2-one

IUPAC name

6-[(4-{methyl[3-(propan-2-yloxy)propyl]amino}piperidin-1-yl)sulfonyl]-12-dihydroquinolin-2-one

SMILES

CC(C)OCCCN(C)C(CC1)CCN1S(c(cc1)cc(C=C2)c1NC2=O)(=O)=O

InChI

InChI=1S/C21H31N3O4S/c1-16(2)28-14-4-11-23(3)18-9-12-24(13-10-18)29(26,27)19-6-7-20-17(15-19)5-8-21(25)22-20/h5-8,15-16,18H,4,9-14H2,1-3H3,(H,22,25)

InChI Key

FHUJSGDOJUHHIY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040734

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.277

Distribution Coefficient, logD

0.463

Water Solubility, LogSw

-3.05

Polar Surface Area

66.817

Acid Dissociation Constant (pKa)

9.24

Base Dissociation Constant (pKb)

9.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.10

G852-0205 in Drug Discovery

Included in Screening Libraries

Bromodomain Modulators Library (5801 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G852-0205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G852-0205?
Check Price and Availability of G852-0205, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G852-0205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G852-0205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G852-0205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G852-0205 available by request