G853-0074 Screening compound: 1-[2-oxo-2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-1,2-dihydroquinolin-2-one

G853-0074 Screening compound: 1-[2-oxo-2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-1,2-dihydroquinolin-2-one
G853-0074 Screening compound: 1-[2-oxo-2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-1,2-dihydroquinolin-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G853-0074
1-[2-oxo-2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-1,2-dihydroquinolin-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G853-0074

Molecular Formula

C26H27N3O4S (C26 H27 N3 O4 S)

Compound Name

1-[2-oxo-2-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-1,2-dihydroquinolin-2-one

IUPAC name

1-[2-oxo-2-(4-phenyl-1236-tetrahydropyridin-1-yl)ethyl]-6-(pyrrolidine-1-sulfonyl)-12-dihydroquinolin-2-one

SMILES

O=C(CN(c(cc1)c(C=C2)cc1S(N1CCCC1)(=O)=O)C2=O)N(CC1)CC=C1c1ccccc1

InChI

InChI=1S/C26H27N3O4S/c30-25-11-8-22-18-23(34(32,33)28-14-4-5-15-28)9-10-24(22)29(25)19-26(31)27-16-12-21(13-17-27)20-6-2-1-3-7-20/h1-3,6-12,18H,4-5,13-17,19H2

InChI Key

ZWODTEQHXVYGTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15040857

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.58

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.183

Distribution Coefficient, logD

3.183

Water Solubility, LogSw

-3.65

Polar Surface Area

63.817

Acid Dissociation Constant (pKa)

21.56

Base Dissociation Constant (pKb)

-2.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

G853-0074 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G853-0074 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G853-0074?
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What is the minimum amount of G853-0074 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G853-0074
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G853-0074
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G853-0074 available by request