G856-8214 Screening compound: 3,4-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}benzamide

G856-8214 Screening compound: 3,4-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}benzamide
G856-8214 Screening compound: 3,4-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G856-8214
3,4-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G856-8214

Molecular Formula

C21H18F2N4O2S (C21 H18 F2 N4 O2 S)

Compound Name

3,4-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[1,2,4]triazolo[3,2-b][1,3]thiazol-5-yl]ethyl}benzamide

IUPAC name

34-difluoro-N-{2-[2-(4-methoxyphenyl)-6-methyl-[124]triazolo[32-b][13]thiazol-5-yl]ethyl}benzamide

SMILES

Cc1c(CCNC(c(cc2)cc(F)c2F)=O)sc2nc(-c(cc3)ccc3OC)nn12

InChI

InChI=1S/C21H18F2N4O2S/c1-12-18(9-10-24-20(28)14-5-8-16(22)17(23)11-14)30-21-25-19(26-27(12)21)13-3-6-15(29-2)7-4-13/h3-8,11H,9-10H2,1-2H3,(H,24,28)

InChI Key

DYCLHIUTLNJMJW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06749954

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.143

Distribution Coefficient, logD

4.142

Water Solubility, LogSw

-4.32

Polar Surface Area

53.507

Acid Dissociation Constant (pKa)

11.57

Base Dissociation Constant (pKb)

3.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.00

G856-8214 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G856-8214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G856-8214?
Check Price and Availability of G856-8214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G856-8214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G856-8214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G856-8214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G856-8214 available by request