G857-0891 Screening compound: N-(2-fluorophenyl)-2-({1,3,6-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetamide

G857-0891 Screening compound: N-(2-fluorophenyl)-2-({1,3,6-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetamide
G857-0891 Screening compound: N-(2-fluorophenyl)-2-({1,3,6-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-0891
N-(2-fluorophenyl)-2-({1,3,6-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-0891

Molecular Formula

C18H17FN4O3S (C18 H17 FN4 O3 S)

Compound Name

N-(2-fluorophenyl)-2-({1,3,6-trimethyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetamide

IUPAC name

N-(2-fluorophenyl)-2-({136-trimethyl-24-dioxo-1H2H3H4H-pyrido[23-d]pyrimidin-5-yl}sulfanyl)acetamide

SMILES

Cc(c(SCC(Nc(cccc1)c1F)=O)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C18H17FN4O3S/c1-10-8-20-16-14(17(25)23(3)18(26)22(16)2)15(10)27-9-13(24)21-12-7-5-4-6-11(12)19/h4-8H,9H2,1-3H3,(H,21,24)

InChI Key

ORNFKGLOIVENDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07654339

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.443

Distribution Coefficient, logD

2.442

Water Solubility, LogSw

-2.63

Polar Surface Area

63.942

Acid Dissociation Constant (pKa)

10.87

Base Dissociation Constant (pKb)

4.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G857-0891 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G857-0891 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-0891?
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What is the minimum amount of G857-0891 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-0891
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-0891
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-0891 available by request