G857-1016 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

G857-1016 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione
G857-1016 Screening compound: 5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1016
5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1016

Molecular Formula

C18H18ClN3O2S (C18 H18 ClN3 O2 S)

Compound Name

5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione

IUPAC name

5-{[(2-chlorophenyl)methyl]sulfanyl}-6-ethyl-13-dimethyl-1H2H3H4H-pyrido[23-d]pyrimidine-24-dione

SMILES

CCc(c(SCc(cccc1)c1Cl)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C18H18ClN3O2S/c1-4-11-9-20-16-14(17(23)22(3)18(24)21(16)2)15(11)25-10-12-7-5-6-8-13(12)19/h5-9H,4,10H2,1-3H3

InChI Key

PHLOXPMLXSLXOH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07654452

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.88

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.297

Distribution Coefficient, logD

4.295

Water Solubility, LogSw

-4.58

Polar Surface Area

41.490

Acid Dissociation Constant (pKa)

23.58

Base Dissociation Constant (pKb)

5.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

G857-1016 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G857-1016 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1016?
Check Price and Availability of G857-1016, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1016 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1016
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1016
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1016 available by request