G857-1059 Screening compound: 2-({1,3-dimethyl-2,4-dioxo-6-propyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetonitrile

G857-1059 Screening compound: 2-({1,3-dimethyl-2,4-dioxo-6-propyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetonitrile
G857-1059 Screening compound: 2-({1,3-dimethyl-2,4-dioxo-6-propyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetonitrile alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1059
2-({1,3-dimethyl-2,4-dioxo-6-propyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetonitrile

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1059

Molecular Formula

C14H16N4O2S (C14 H16 N4 O2 S)

Compound Name

2-({1,3-dimethyl-2,4-dioxo-6-propyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-5-yl}sulfanyl)acetonitrile

IUPAC name

2-({13-dimethyl-24-dioxo-6-propyl-1H2H3H4H-pyrido[23-d]pyrimidin-5-yl}sulfanyl)acetonitrile

SMILES

CCCc(c(SCC#N)c1C(N2C)=O)cnc1N(C)C2=O

InChI

InChI=1S/C14H16N4O2S/c1-4-5-9-8-16-12-10(11(9)21-7-6-15)13(19)18(3)14(20)17(12)2/h8H,4-5,7H2,1-3H3

InChI Key

FSLYKQJPYOAZAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07807367

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

304.37

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.224

Distribution Coefficient, logD

2.223

Water Solubility, LogSw

-1.99

Polar Surface Area

59.254

Acid Dissociation Constant (pKa)

23.49

Base Dissociation Constant (pKb)

4.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

G857-1059 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G857-1059 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1059?
Check Price and Availability of G857-1059, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1059 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1059
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1059
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1059 available by request