G857-1658 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,5-dimethoxybenzene-1-sulfonamide

G857-1658 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,5-dimethoxybenzene-1-sulfonamide
G857-1658 Screening compound: N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,5-dimethoxybenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1658
N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,5-dimethoxybenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1658

Molecular Formula

C20H20FNO6S3 (C20 H20 FNO6 S3)

Compound Name

N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-2,5-dimethoxybenzene-1-sulfonamide

IUPAC name

N-[2-(4-fluorobenzenesulfonyl)-2-(thiophen-2-yl)ethyl]-25-dimethoxybenzene-1-sulfonamide

SMILES

COc(cc1)cc(S(NCC(c2cccs2)S(c(cc2)ccc2F)(=O)=O)(=O)=O)c1OC

InChI

InChI=1S/C20H20FNO6S3/c1-27-15-7-10-17(28-2)19(12-15)31(25,26)22-13-20(18-4-3-11-29-18)30(23,24)16-8-5-14(21)6-9-16/h3-12,20,22H,13H2,1-2H3/t20-/m0/s1

InChI Key

PUPWHPBOHRTPTM-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD06748740

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.407

Distribution Coefficient, logD

3.406

Water Solubility, LogSw

-3.78

Polar Surface Area

87.690

Acid Dissociation Constant (pKa)

10.77

Base Dissociation Constant (pKb)

-7.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

G857-1658 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G857-1658 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1658?
Check Price and Availability of G857-1658, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1658 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1658
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1658
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1658 available by request