G857-1805 Screening compound: 5-[(2,6-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

G857-1805 Screening compound: 5-[(2,6-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol
G857-1805 Screening compound: 5-[(2,6-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1805
5-[(2,6-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1805

Molecular Formula

C21H21FN4O3S (C21 H21 FN4 O3 S)

Compound Name

5-[(2,6-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

IUPAC name

5-[(26-dimethylmorpholin-4-yl)(2-fluorophenyl)methyl]-2-(furan-2-yl)-[124]triazolo[32-b][13]thiazol-6-ol

SMILES

CC(C1)OC(C)CN1C(c(sc1nc(-c2ccco2)nn11)c1O)c(cccc1)c1F

InChI

InChI=1S/C21H21FN4O3S/c1-12-10-25(11-13(2)29-12)17(14-6-3-4-7-15(14)22)18-20(27)26-21(30-18)23-19(24-26)16-8-5-9-28-16/h3-9,12-13,17,27H,10-11H2,1-2H3

InChI Key

VBUOBYPBOLJFIT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06749127

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.189

Distribution Coefficient, logD

0.130

Water Solubility, LogSw

-3.14

Polar Surface Area

55.404

Acid Dissociation Constant (pKa)

4.34

Base Dissociation Constant (pKb)

6.48

Number of Chiral Centers

3.00

Percent sp3 carbon bonding

33.30

G857-1805 in Drug Discovery

Included in Screening Libraries

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with G857-1805 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1805?
Check Price and Availability of G857-1805, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1805 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1805
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1805
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1805 available by request