G857-1881 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

G857-1881 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol
G857-1881 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1881
5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1881

Molecular Formula

C26H24FN5O2S (C26 H24 FN5 O2 S)

Compound Name

5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

IUPAC name

5-{[4-(2-fluorophenyl)piperazin-1-yl](4-methylphenyl)methyl}-2-(furan-2-yl)-[124]triazolo[32-b][13]thiazol-6-ol

SMILES

Cc1ccc(C(c(sc2nc(-c3ccco3)nn22)c2O)N(CC2)CCN2c(cccc2)c2F)cc1

InChI

InChI=1S/C26H24FN5O2S/c1-17-8-10-18(11-9-17)22(31-14-12-30(13-15-31)20-6-3-2-5-19(20)27)23-25(33)32-26(35-23)28-24(29-32)21-7-4-16-34-21/h2-11,16,22,33H,12-15H2,1H3/t22-/m1/s1

InChI Key

JVDHBNKYHWTVHP-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD07192764

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.941

Distribution Coefficient, logD

1.882

Water Solubility, LogSw

-4.49

Polar Surface Area

51.431

Acid Dissociation Constant (pKa)

4.34

Base Dissociation Constant (pKb)

7.31

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.10

References: we are preparing a list of scientific research reports with G857-1881 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1881?
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What is the minimum amount of G857-1881 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1881
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1881
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1881 available by request