G857-1927 Screening compound: 5-[(2,4-dichlorophenyl)(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

G857-1927 Screening compound: 5-[(2,4-dichlorophenyl)(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol
G857-1927 Screening compound: 5-[(2,4-dichlorophenyl)(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1927
5-[(2,4-dichlorophenyl)(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1927

Molecular Formula

C24H18Cl2N4O2S (C24 H18 Cl2 N4 O2 S)

Compound Name

5-[(2,4-dichlorophenyl)(1,2,3,4-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

IUPAC name

5-[(24-dichlorophenyl)(1234-tetrahydroisoquinolin-2-yl)methyl]-2-(furan-2-yl)-[124]triazolo[32-b][13]thiazol-6-ol

SMILES

Oc1c(C(c(ccc(Cl)c2)c2Cl)N(CC2)Cc3c2cccc3)sc2nc(-c3ccco3)nn12

InChI

InChI=1S/C24H18Cl2N4O2S/c25-16-7-8-17(18(26)12-16)20(29-10-9-14-4-1-2-5-15(14)13-29)21-23(31)30-24(33-21)27-22(28-30)19-6-3-11-32-19/h1-8,11-12,20,31H,9-10,13H2/t20-/m1/s1

InChI Key

HXTWVAYYBDDBFZ-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD06749215

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

6.059

Distribution Coefficient, logD

2.999

Water Solubility, LogSw

-5.84

Polar Surface Area

48.134

Acid Dissociation Constant (pKa)

4.34

Base Dissociation Constant (pKb)

6.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

G857-1927 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G857-1927 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1927?
Check Price and Availability of G857-1927, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1927 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1927
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1927
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1927 available by request