G857-1939 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

G857-1939 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol
G857-1939 Screening compound: 5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1939
5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1939

Molecular Formula

C23H20FN5O2S2 (C23 H20 FN5 O2 S2)

Compound Name

5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

IUPAC name

5-{[4-(2-fluorophenyl)piperazin-1-yl](thiophen-2-yl)methyl}-2-(furan-2-yl)-[124]triazolo[32-b][13]thiazol-6-ol

SMILES

Oc1c(C(c2cccs2)N(CC2)CCN2c(cccc2)c2F)sc2nc(-c3ccco3)nn12

InChI

InChI=1S/C23H20FN5O2S2/c24-15-5-1-2-6-16(15)27-9-11-28(12-10-27)19(18-8-4-14-32-18)20-22(30)29-23(33-20)25-21(26-29)17-7-3-13-31-17/h1-8,13-14,19,30H,9-12H2/t19-/m0/s1

InChI Key

DRFODKSWDURCSO-IBGZPJMESA-N

MDL Number (MFCD)

MFCD07646119

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

481.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.142

Distribution Coefficient, logD

1.050

Water Solubility, LogSw

-4.19

Polar Surface Area

52.450

Acid Dissociation Constant (pKa)

4.31

Base Dissociation Constant (pKb)

6.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.70

G857-1939 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G857-1939 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1939?
Check Price and Availability of G857-1939, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-1939 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1939
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1939
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1939 available by request