G857-1955 Screening compound: 2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

G857-1955 Screening compound: 2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol
G857-1955 Screening compound: 2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-1955
2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-1955

Molecular Formula

C24H23N5O4S (C24 H23 N5 O4 S)

Compound Name

2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[1,2,4]triazolo[3,2-b][1,3]thiazol-6-ol

IUPAC name

2-(furan-2-yl)-5-[(furan-2-yl)[4-(4-methoxyphenyl)piperazin-1-yl]methyl]-[124]triazolo[32-b][13]thiazol-6-ol

SMILES

COc(cc1)ccc1N(CC1)CCN1C(c1ccco1)c(sc1nc(-c2ccco2)nn11)c1O

InChI

InChI=1S/C24H23N5O4S/c1-31-17-8-6-16(7-9-17)27-10-12-28(13-11-27)20(18-4-2-14-32-18)21-23(30)29-24(34-21)25-22(26-29)19-5-3-15-33-19/h2-9,14-15,20,30H,10-13H2,1H3/t20-/m0/s1

InChI Key

PBWZCDHUUDBBKY-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD07646129

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.644

Distribution Coefficient, logD

0.552

Water Solubility, LogSw

-3.82

Polar Surface Area

67.855

Acid Dissociation Constant (pKa)

4.31

Base Dissociation Constant (pKb)

6.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

G857-1955 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G857-1955 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-1955?
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What is the minimum amount of G857-1955 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-1955
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-1955
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-1955 available by request