G857-2151 Screening compound: 1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

G857-2151 Screening compound: 1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine
G857-2151 Screening compound: 1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-2151
1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-2151

Molecular Formula

C20H19N3O4S (C20 H19 N3 O4 S)

Compound Name

1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

IUPAC name

1-(4-methylphenyl)-2-(4-nitrobenzenesulfonyl)-1H2H3H4H-pyrrolo[12-a]pyrazine

SMILES

Cc1ccc(C(c2cccn2CC2)N2S(c(cc2)ccc2[N+]([O-])=O)(=O)=O)cc1

InChI

InChI=1S/C20H19N3O4S/c1-15-4-6-16(7-5-15)20-19-3-2-12-21(19)13-14-22(20)28(26,27)18-10-8-17(9-11-18)23(24)25/h2-12,20H,13-14H2,1H3/t20-/m1/s1

InChI Key

OUHQNHUVSMVCDX-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD07651684

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.310

Distribution Coefficient, logD

4.310

Water Solubility, LogSw

-4.24

Polar Surface Area

67.582

Acid Dissociation Constant (pKa)

24.35

Base Dissociation Constant (pKb)

-4.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

20.00

G857-2151 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Human Proteases Annotated Library (2868 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with G857-2151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-2151?
Check Price and Availability of G857-2151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-2151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-2151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-2151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-2151 available by request