G857-2160 Screening compound: 1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

G857-2160 Screening compound: 1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine
G857-2160 Screening compound: 1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G857-2160
1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G857-2160

Molecular Formula

C21H19F3N2O2S (C21 H19 F3 N2 O2 S)

Compound Name

1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazine

IUPAC name

1-(4-methylphenyl)-2-[3-(trifluoromethyl)benzenesulfonyl]-1H2H3H4H-pyrrolo[12-a]pyrazine

SMILES

Cc1ccc(C(c2cccn2CC2)N2S(c2cc(C(F)(F)F)ccc2)(=O)=O)cc1

InChI

InChI=1S/C21H19F3N2O2S/c1-15-7-9-16(10-8-15)20-19-6-3-11-25(19)12-13-26(20)29(27,28)18-5-2-4-17(14-18)21(22,23)24/h2-11,14,20H,12-13H2,1H3/t20-/m1/s1

InChI Key

RPCSMCHMAVWHPU-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD07651693

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.207

Distribution Coefficient, logD

5.207

Water Solubility, LogSw

-5.23

Polar Surface Area

34.200

Acid Dissociation Constant (pKa)

24.35

Base Dissociation Constant (pKb)

-4.65

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

G857-2160 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with G857-2160 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G857-2160?
Check Price and Availability of G857-2160, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G857-2160 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G857-2160
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G857-2160
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G857-2160 available by request