G859-0299 Screening compound: 3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-3,4-dihydroquinazolin-4-one

G859-0299 Screening compound: 3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-3,4-dihydroquinazolin-4-one
G859-0299 Screening compound: 3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-3,4-dihydroquinazolin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G859-0299
3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-3,4-dihydroquinazolin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G859-0299

Molecular Formula

C29H29N3O3S (C29 H29 N3 O3 S)

Compound Name

3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-3,4-dihydroquinazolin-4-one

IUPAC name

3-(3-methoxyphenyl)-2-{[(2-methylphenyl)methyl]sulfanyl}-7-(piperidine-1-carbonyl)-34-dihydroquinazolin-4-one

SMILES

Cc1c(CSC(N2c3cc(OC)ccc3)=Nc(cc(cc3)C(N4CCCCC4)=O)c3C2=O)cccc1

InChI

InChI=1S/C29H29N3O3S/c1-20-9-4-5-10-22(20)19-36-29-30-26-17-21(27(33)31-15-6-3-7-16-31)13-14-25(26)28(34)32(29)23-11-8-12-24(18-23)35-2/h4-5,8-14,17-18H,3,6-7,15-16,19H2,1-2H3

InChI Key

MHZJMWVBMIUJCA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15042055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.289

Distribution Coefficient, logD

5.289

Water Solubility, LogSw

-5.15

Polar Surface Area

49.352

Acid Dissociation Constant (pKa)

27.87

Base Dissociation Constant (pKb)

4.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.60

G859-0299 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G859-0299 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G859-0299?
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What is the minimum amount of G859-0299 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G859-0299
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G859-0299
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G859-0299 available by request