G860-0227 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one

G860-0227 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one
G860-0227 Screening compound: 6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G860-0227
6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G860-0227

Molecular Formula

C22H21FN6O2 (C22 H21 FN6 O2)

Compound Name

6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H,6H-[1,2,4]triazolo[1,5-c]quinazolin-5-one

IUPAC name

6-{2-[4-(2-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-2-methyl-5H6H-[124]triazolo[15-c]quinazolin-5-one

SMILES

Cc(nc1-c(cccc2)c2N2CC(N(CC3)CCN3c(cccc3)c3F)=O)nn1C2=O

InChI

InChI=1S/C22H21FN6O2/c1-15-24-21-16-6-2-4-8-18(16)28(22(31)29(21)25-15)14-20(30)27-12-10-26(11-13-27)19-9-5-3-7-17(19)23/h2-9H,10-14H2,1H3

InChI Key

SMBLENYNHHTJEC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15072202

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.031

Distribution Coefficient, logD

2.031

Water Solubility, LogSw

-2.73

Polar Surface Area

58.331

Acid Dissociation Constant (pKa)

20.62

Base Dissociation Constant (pKb)

4.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G860-0227 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G860-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G860-0227?
Check Price and Availability of G860-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G860-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G860-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G860-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G860-0227 available by request