G863-0066 Screening compound: 5-bromo-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)pyridine-3-carboxamide

G863-0066 Screening compound: 5-bromo-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)pyridine-3-carboxamide
G863-0066 Screening compound: 5-bromo-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0066
5-bromo-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0066

Molecular Formula

C18H15BrN4OS (C18 H15 BrN4 OS)

Compound Name

5-bromo-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)pyridine-3-carboxamide

IUPAC name

5-bromo-N-({6-phenyl-2H3H-imidazo[21-b][13]thiazol-5-yl}methyl)pyridine-3-carboxamide

SMILES

O=C(c1cc(Br)cnc1)NCc1c(-c2ccccc2)nc2SCCn12

InChI

InChI=1S/C18H15BrN4OS/c19-14-8-13(9-20-10-14)17(24)21-11-15-16(12-4-2-1-3-5-12)22-18-23(15)6-7-25-18/h1-5,8-10H,6-7,11H2,(H,21,24)

InChI Key

AMXOQSZOABZHGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09238935

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.31

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.366

Distribution Coefficient, logD

3.280

Water Solubility, LogSw

-3.45

Polar Surface Area

45.239

Acid Dissociation Constant (pKa)

9.86

Base Dissociation Constant (pKb)

6.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G863-0066 in Drug Discovery

Included in Screening Libraries

Immunological Library (6760 compounds)

Targeted Diversity Library (40567 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Ion Channels Focused Library (26372 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
  • Cancer
Targets:
  • Others
  • Ion Channels
Mechanism of action:
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G863-0066 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0066?
Check Price and Availability of G863-0066, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0066 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0066
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0066
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0066 available by request