G863-0187 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

G863-0187 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide
G863-0187 Screening compound: N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0187
N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0187

Molecular Formula

C17H21N3OS (C17 H21 N3 OS)

Compound Name

N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

IUPAC name

N-{[6-(4-methylphenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}butanamide

SMILES

CCCC(NCc1c(-c2ccc(C)cc2)nc2SCCn12)=O

InChI

InChI=1S/C17H21N3OS/c1-3-4-15(21)18-11-14-16(13-7-5-12(2)6-8-13)19-17-20(14)9-10-22-17/h5-8H,3-4,9-11H2,1-2H3,(H,18,21)

InChI Key

KTKVMHCLRZHXDQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09238964

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

315.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.369

Distribution Coefficient, logD

1.877

Water Solubility, LogSw

-3.39

Polar Surface Area

35.690

Acid Dissociation Constant (pKa)

12.41

Base Dissociation Constant (pKb)

8.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.20

G863-0187 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0187 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0187?
Check Price and Availability of G863-0187, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0187 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0187
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0187
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0187 available by request