G863-0263 Screening compound: 2-ethyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

G863-0263 Screening compound: 2-ethyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide
G863-0263 Screening compound: 2-ethyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0263
2-ethyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0263

Molecular Formula

C18H22FN3OS (C18 H22 FN3 OS)

Compound Name

2-ethyl-N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}butanamide

IUPAC name

2-ethyl-N-{[6-(4-fluorophenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}butanamide

SMILES

CCC(CC)C(NCc1c(-c(cc2)ccc2F)nc2SCCn12)=O

InChI

InChI=1S/C18H22FN3OS/c1-3-12(4-2)17(23)20-11-15-16(13-5-7-14(19)8-6-13)21-18-22(15)9-10-24-18/h5-8,12H,3-4,9-11H2,1-2H3,(H,20,23)

InChI Key

GDVCZWRENOHVDB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239009

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.597

Distribution Coefficient, logD

3.178

Water Solubility, LogSw

-3.58

Polar Surface Area

35.903

Acid Dissociation Constant (pKa)

11.96

Base Dissociation Constant (pKb)

7.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

G863-0263 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0263?
Check Price and Availability of G863-0263, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0263 available by request