G863-0330 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-2-phenoxyacetamide

G863-0330 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-2-phenoxyacetamide
G863-0330 Screening compound: N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-2-phenoxyacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0330
N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-2-phenoxyacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0330

Molecular Formula

C20H18ClN3O2S (C20 H18 ClN3 O2 S)

Compound Name

N-{[6-(4-chlorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-2-phenoxyacetamide

IUPAC name

N-{[6-(4-chlorophenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}-2-phenoxyacetamide

SMILES

O=C(COc1ccccc1)NCc1c(-c(cc2)ccc2Cl)nc2SCCn12

InChI

InChI=1S/C20H18ClN3O2S/c21-15-8-6-14(7-9-15)19-17(24-10-11-27-20(24)23-19)12-22-18(25)13-26-16-4-2-1-3-5-16/h1-9H,10-13H2,(H,22,25)

InChI Key

FTVUVDHLUXHEBL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165040

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.014

Distribution Coefficient, logD

3.211

Water Solubility, LogSw

-4.58

Polar Surface Area

42.917

Acid Dissociation Constant (pKa)

12.55

Base Dissociation Constant (pKb)

8.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G863-0330 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0330 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0330?
Check Price and Availability of G863-0330, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0330 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0330
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0330
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0330 available by request