G863-0396 Screening compound: 3-methoxy-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)benzamide

G863-0396 Screening compound: 3-methoxy-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)benzamide
G863-0396 Screening compound: 3-methoxy-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0396
3-methoxy-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0396

Molecular Formula

C20H19N3O2S (C20 H19 N3 O2 S)

Compound Name

3-methoxy-N-({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methyl)benzamide

IUPAC name

3-methoxy-N-({6-phenyl-2H3H-imidazo[21-b][13]thiazol-5-yl}methyl)benzamide

SMILES

COc1cccc(C(NCc2c(-c3ccccc3)nc3SCCn23)=O)c1

InChI

InChI=1S/C20H19N3O2S/c1-25-16-9-5-8-15(12-16)19(24)21-13-17-18(14-6-3-2-4-7-14)22-20-23(17)10-11-26-20/h2-9,12H,10-11,13H2,1H3,(H,21,24)

InChI Key

TXEVNIDDCZNMKA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.513

Distribution Coefficient, logD

3.428

Water Solubility, LogSw

-3.83

Polar Surface Area

43.175

Acid Dissociation Constant (pKa)

11.70

Base Dissociation Constant (pKb)

6.74

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G863-0396 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
  • Cancer
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0396 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0396?
Check Price and Availability of G863-0396, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0396 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0396
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0396
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0396 available by request