G863-0398 Screening compound: 3-methoxy-N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}benzamide

G863-0398 Screening compound: 3-methoxy-N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}benzamide
G863-0398 Screening compound: 3-methoxy-N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0398
3-methoxy-N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0398

Molecular Formula

C21H21N3O2S (C21 H21 N3 O2 S)

Compound Name

3-methoxy-N-{[6-(4-methylphenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}benzamide

IUPAC name

3-methoxy-N-{[6-(4-methylphenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}benzamide

SMILES

Cc(cc1)ccc1-c1c(CNC(c2cc(OC)ccc2)=O)n(CCS2)c2n1

InChI

InChI=1S/C21H21N3O2S/c1-14-6-8-15(9-7-14)19-18(24-10-11-27-21(24)23-19)13-22-20(25)16-4-3-5-17(12-16)26-2/h3-9,12H,10-11,13H2,1-2H3,(H,22,25)

InChI Key

CNPMPEXVYCEATB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.48

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.042

Distribution Coefficient, logD

3.696

Water Solubility, LogSw

-4.05

Polar Surface Area

43.175

Acid Dissociation Constant (pKa)

11.70

Base Dissociation Constant (pKb)

7.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

G863-0398 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
  • Cancer
Targets:
  • Ion Channels
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0398 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0398?
Check Price and Availability of G863-0398, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G863-0398 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0398
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0398
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0398 available by request