G863-0399 Screening compound: N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-3-methoxybenzamide

G863-0399 Screening compound: N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-3-methoxybenzamide
G863-0399 Screening compound: N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-3-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G863-0399
N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-3-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G863-0399

Molecular Formula

C20H18FN3O2S (C20 H18 FN3 O2 S)

Compound Name

N-{[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]methyl}-3-methoxybenzamide

IUPAC name

N-{[6-(4-fluorophenyl)-2H3H-imidazo[21-b][13]thiazol-5-yl]methyl}-3-methoxybenzamide

SMILES

COc1cccc(C(NCc2c(-c(cc3)ccc3F)nc3SCCn23)=O)c1

InChI

InChI=1S/C20H18FN3O2S/c1-26-16-4-2-3-14(11-16)19(25)22-12-17-18(13-5-7-15(21)8-6-13)23-20-24(17)9-10-27-20/h2-8,11H,9-10,12H2,1H3,(H,22,25)

InChI Key

XYKLPXPUIYCEGY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09239070

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.647

Distribution Coefficient, logD

3.620

Water Solubility, LogSw

-3.99

Polar Surface Area

43.175

Acid Dissociation Constant (pKa)

11.70

Base Dissociation Constant (pKb)

6.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G863-0399 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G863-0399 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G863-0399?
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What is the minimum amount of G863-0399 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G863-0399
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G863-0399
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G863-0399 available by request