G866-0243 Screening compound: 2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one

G866-0243 Screening compound: 2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one
G866-0243 Screening compound: 2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G866-0243
2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G866-0243

Molecular Formula

C25H27N7O2 (C25 H27 N7 O2)

Compound Name

2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one

IUPAC name

2-(4-ethoxyphenyl)-1-{4-[3-(4-methylphenyl)-3H-[123]triazolo[45-d]pyrimidin-7-yl]piperazin-1-yl}ethan-1-one

SMILES

CCOc1ccc(CC(N(CC2)CCN2c2ncnc3c2nnn3-c2ccc(C)cc2)=O)cc1

InChI

InChI=1S/C25H27N7O2/c1-3-34-21-10-6-19(7-11-21)16-22(33)30-12-14-31(15-13-30)24-23-25(27-17-26-24)32(29-28-23)20-8-4-18(2)5-9-20/h4-11,17H,3,12-16H2,1-2H3

InChI Key

GLRSASVUOGLYEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08343457

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.707

Distribution Coefficient, logD

3.707

Water Solubility, LogSw

-3.75

Polar Surface Area

73.678

Acid Dissociation Constant (pKa)

18.21

Base Dissociation Constant (pKb)

3.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

G866-0243 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G866-0243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G866-0243?
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What is the minimum amount of G866-0243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G866-0243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G866-0243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G866-0243 available by request