G867-0223 Screening compound: N-{4-[(4-{3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide

G867-0223 Screening compound: N-{4-[(4-{3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide
G867-0223 Screening compound: N-{4-[(4-{3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G867-0223
N-{4-[(4-{3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G867-0223

Molecular Formula

C23H24N8O3S (C23 H24 N8 O3 S)

Compound Name

N-{4-[(4-{3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide

IUPAC name

N-{4-[(4-{3-benzyl-3H-[123]triazolo[45-d]pyrimidin-7-yl}piperazin-1-yl)sulfonyl]phenyl}acetamide

SMILES

CC(Nc(cc1)ccc1S(N(CC1)CCN1c1ncnc2c1nnn2Cc1ccccc1)(=O)=O)=O

InChI

InChI=1S/C23H24N8O3S/c1-17(32)26-19-7-9-20(10-8-19)35(33,34)30-13-11-29(12-14-30)22-21-23(25-16-24-22)31(28-27-21)15-18-5-3-2-4-6-18/h2-10,16H,11-15H2,1H3,(H,26,32)

InChI Key

VNZWLMYKHMBATA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08344842

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.56

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

11

Partition Coefficient, logP

2.001

Distribution Coefficient, logD

2.000

Water Solubility, LogSw

-2.63

Polar Surface Area

105.270

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

G867-0223 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G867-0223 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G867-0223?
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What is the minimum amount of G867-0223 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G867-0223
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G867-0223
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G867-0223 available by request