G868-0705 Screening compound: 4-{2-[4-(2,6-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine

G868-0705 Screening compound: 4-{2-[4-(2,6-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine
G868-0705 Screening compound: 4-{2-[4-(2,6-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G868-0705
4-{2-[4-(2,6-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G868-0705

Molecular Formula

C20H23F2N5O2 (C20 H23 F2 N5 O2)

Compound Name

4-{2-[4-(2,6-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine

IUPAC name

4-{2-[4-(26-difluorobenzoyl)piperazin-1-yl]-6-methylpyrimidin-4-yl}morpholine

SMILES

Cc1nc(N(CC2)CCN2C(c(c(F)ccc2)c2F)=O)nc(N2CCOCC2)c1

InChI

InChI=1S/C20H23F2N5O2/c1-14-13-17(25-9-11-29-12-10-25)24-20(23-14)27-7-5-26(6-8-27)19(28)18-15(21)3-2-4-16(18)22/h2-4,13H,5-12H2,1H3

InChI Key

WTJPQCBQTUVDRW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09237949

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.959

Distribution Coefficient, logD

2.931

Water Solubility, LogSw

-3.01

Polar Surface Area

48.276

Acid Dissociation Constant (pKa)

21.00

Base Dissociation Constant (pKb)

6.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

G868-0705 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

PI3K-Targeted Library (17255 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G868-0705 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G868-0705?
Check Price and Availability of G868-0705, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G868-0705 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G868-0705
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G868-0705
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G868-0705 available by request