G869-1015 Screening compound: 2,4-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide

G869-1015 Screening compound: 2,4-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide
G869-1015 Screening compound: 2,4-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G869-1015
2,4-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G869-1015

Molecular Formula

C25H25N5O2S (C25 H25 N5 O2 S)

Compound Name

2,4-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide

IUPAC name

24-dimethyl-N-(4-{[4-methyl-6-(phenylamino)pyrimidin-2-yl]amino}phenyl)benzene-1-sulfonamide

SMILES

Cc(cc1)cc(C)c1S(Nc(cc1)ccc1Nc1nc(Nc2ccccc2)cc(C)n1)(=O)=O

InChI

InChI=1S/C25H25N5O2S/c1-17-9-14-23(18(2)15-17)33(31,32)30-22-12-10-21(11-13-22)28-25-26-19(3)16-24(29-25)27-20-7-5-4-6-8-20/h4-16,30H,1-3H3,(H2,26,27,28,29)

InChI Key

PPUWFBPRJKKDFZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09238577

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.147

Distribution Coefficient, logD

5.297

Water Solubility, LogSw

-5.51

Polar Surface Area

78.792

Acid Dissociation Constant (pKa)

8.21

Base Dissociation Constant (pKb)

8.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.00

G869-1015 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G869-1015 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G869-1015?
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What is the minimum amount of G869-1015 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G869-1015
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G869-1015
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G869-1015 available by request