G883-0159 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide

G883-0159 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide
G883-0159 Screening compound: N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0159
N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0159

Molecular Formula

C16H20N2O2 (C16 H20 N2 O2)

Compound Name

N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide

IUPAC name

N-[(1-propanoyl-23-dihydro-1H-indol-5-yl)methyl]cyclopropanecarboxamide

SMILES

CCC(N(CC1)c2c1cc(CNC(C1CC1)=O)cc2)=O

InChI

InChI=1S/C16H20N2O2/c1-2-15(19)18-8-7-13-9-11(3-6-14(13)18)10-17-16(20)12-4-5-12/h3,6,9,12H,2,4-5,7-8,10H2,1H3,(H,17,20)

InChI Key

NNVBBCIBQSAHDJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165271

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

272.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.815

Distribution Coefficient, logD

1.815

Water Solubility, LogSw

-2.25

Polar Surface Area

40.598

Acid Dissociation Constant (pKa)

14.08

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G883-0159 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0159 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0159?
Check Price and Availability of G883-0159, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0159 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0159
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0159
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0159 available by request