G883-0227 Screening compound: 4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzamide

G883-0227 Screening compound: 4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzamide
G883-0227 Screening compound: 4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0227
4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0227

Molecular Formula

C25H27N3O2 (C25 H27 N3 O2)

Compound Name

4-(2,5-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-2,3-dihydro-1H-indol-5-yl)methyl]benzamide

IUPAC name

4-(25-dimethyl-1H-pyrrol-1-yl)-N-[(1-propanoyl-23-dihydro-1H-indol-5-yl)methyl]benzamide

SMILES

CCC(N(CC1)c2c1cc(CNC(c(cc1)ccc1-n1c(C)ccc1C)=O)cc2)=O

InChI

InChI=1S/C25H27N3O2/c1-4-24(29)27-14-13-21-15-19(7-12-23(21)27)16-26-25(30)20-8-10-22(11-9-20)28-17(2)5-6-18(28)3/h5-12,15H,4,13-14,16H2,1-3H3,(H,26,30)

InChI Key

OCWAJMLBLZICML-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165315

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

401.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.610

Distribution Coefficient, logD

3.610

Water Solubility, LogSw

-3.72

Polar Surface Area

42.964

Acid Dissociation Constant (pKa)

12.37

Base Dissociation Constant (pKb)

3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G883-0227 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with G883-0227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0227?
Check Price and Availability of G883-0227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0227 available by request