G883-0652 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(diethylsulfamoyl)piperidine-4-carboxamide

G883-0652 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(diethylsulfamoyl)piperidine-4-carboxamide
G883-0652 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(diethylsulfamoyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0652
N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(diethylsulfamoyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0652

Molecular Formula

C26H34N4O4S (C26 H34 N4 O4 S)

Compound Name

N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(diethylsulfamoyl)piperidine-4-carboxamide

IUPAC name

n/a

SMILES

CCN(CC)S(N(CC1)CCC1C(NCc(cc1)cc(CC2)c1N2C(c1ccccc1)=O)=O)(=O)=O

InChI

InChI=1S/C26H34N4O4S/c1-3-28(4-2)35(33,34)29-15-12-21(13-16-29)25(31)27-19-20-10-11-24-23(18-20)14-17-30(24)26(32)22-8-6-5-7-9-22/h5-11,18,21H,3-4,12-17,19H2,1-2H3,(H,27,31)

InChI Key

AQSVMISHQIEHBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165469

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.65

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.158

Distribution Coefficient, logD

2.158

Water Solubility, LogSw

-2.72

Polar Surface Area

73.833

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

G883-0652 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases
  • GPCR

References: we are preparing a list of scientific research reports with G883-0652 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0652?
Check Price and Availability of G883-0652, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0652 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0652
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0652
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0652 available by request