G883-0659 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

G883-0659 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide
G883-0659 Screening compound: N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0659
N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0659

Molecular Formula

C26H32N4O4S (C26 H32 N4 O4 S)

Compound Name

N-[(1-benzoyl-2,3-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

IUPAC name

N-[(1-benzoyl-23-dihydro-1H-indol-5-yl)methyl]-1-(pyrrolidine-1-sulfonyl)piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1S(N1CCCC1)(=O)=O)NCc(cc1)cc(CC2)c1N2C(c1ccccc1)=O

InChI

InChI=1S/C26H32N4O4S/c31-25(21-10-15-29(16-11-21)35(33,34)28-13-4-5-14-28)27-19-20-8-9-24-23(18-20)12-17-30(24)26(32)22-6-2-1-3-7-22/h1-3,6-9,18,21H,4-5,10-17,19H2,(H,27,31)

InChI Key

KQNJIJMXNCYFAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165473

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.63

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.010

Distribution Coefficient, logD

2.010

Water Solubility, LogSw

-2.64

Polar Surface Area

74.813

Acid Dissociation Constant (pKa)

13.43

Base Dissociation Constant (pKb)

-0.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

G883-0659 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Anti-HIV1 Library (19540 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Proteases
  • GPCR

References: we are preparing a list of scientific research reports with G883-0659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0659?
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What is the minimum amount of G883-0659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0659 available by request