G883-0763 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide

G883-0763 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide
G883-0763 Screening compound: N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0763
N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0763

Molecular Formula

C26H25FN2O3 (C26 H25 FN2 O3)

Compound Name

N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide

IUPAC name

N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}-3-(4-methoxyphenyl)propanamide

SMILES

COc1ccc(CCC(NCc(cc2)cc(CC3)c2N3C(c(cc2)ccc2F)=O)=O)cc1

InChI

InChI=1S/C26H25FN2O3/c1-32-23-10-2-18(3-11-23)5-13-25(30)28-17-19-4-12-24-21(16-19)14-15-29(24)26(31)20-6-8-22(27)9-7-20/h2-4,6-12,16H,5,13-15,17H2,1H3,(H,28,30)

InChI Key

FWSXMSPTWLQANX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165536

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.100

Distribution Coefficient, logD

4.100

Water Solubility, LogSw

-4.21

Polar Surface Area

47.661

Acid Dissociation Constant (pKa)

13.47

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

G883-0763 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0763 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0763?
Check Price and Availability of G883-0763, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0763 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0763
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0763
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0763 available by request