G883-0781 Screening compound: 4-ethoxy-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

G883-0781 Screening compound: 4-ethoxy-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide
G883-0781 Screening compound: 4-ethoxy-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G883-0781
4-ethoxy-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G883-0781

Molecular Formula

C25H23FN2O3 (C25 H23 FN2 O3)

Compound Name

4-ethoxy-N-{[1-(4-fluorobenzoyl)-2,3-dihydro-1H-indol-5-yl]methyl}benzamide

IUPAC name

4-ethoxy-N-{[1-(4-fluorobenzoyl)-23-dihydro-1H-indol-5-yl]methyl}benzamide

SMILES

CCOc(cc1)ccc1C(NCc(cc1)cc(CC2)c1N2C(c(cc1)ccc1F)=O)=O

InChI

InChI=1S/C25H23FN2O3/c1-2-31-22-10-6-18(7-11-22)24(29)27-16-17-3-12-23-20(15-17)13-14-28(23)25(30)19-4-8-21(26)9-5-19/h3-12,15H,2,13-14,16H2,1H3,(H,27,29)

InChI Key

MPPVQFSFPWRLFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27165553

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.077

Distribution Coefficient, logD

4.077

Water Solubility, LogSw

-4.05

Polar Surface Area

47.454

Acid Dissociation Constant (pKa)

12.87

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G883-0781 in Drug Discovery

Included in Screening Libraries

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G883-0781 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G883-0781?
Check Price and Availability of G883-0781, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G883-0781 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G883-0781
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G883-0781
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G883-0781 available by request